Cytochrome c catalyses the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxide

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Cytochrome c catalyses the formation of pentyl radical and octanoic acid radical from linoleic acid hydroperoxide.

A reaction of 13-hydroperoxide octadecadienoic acid (13-HPODE) with cytochrome c was analysed using ESR, HPLC-ESR and HPLC-ESR-MS by the combined use of the spin-trapping technique. The ESR, HPLC-ESR and HPLC-ESR-MS analyses showed that cytochrome c catalyses formation of pentyl and octanoic acid radicals from 13-HPODE. On the other hand, only the alpha-(4-pyridyl-1-oxide)-N-t-butylnitrone/octa...

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Some polyphenols inhibit the formation of pentyl radical and octanoic acid radical in the reaction mixture of linoleic acid hydroperoxide with ferrous ions.

Effects of some polyphenols and their related compounds (chlorogenic acid, caffeic acid, quinic acid, ferulic acid, gallic acid, D-(+)-catechin, D-(-)-catechin, 4-hydroxy-3-methoxybenzoic acid, salicylic acid, L-dopa, dopamine, L-adrenaline, L-noradrenaline, o-dihydroxybenzene, m-dihydroxybenzene, and p-dihydroxybenzene) on the formation of 13-hydroperoxide octadecadienoic (13-HPODE) acid-deriv...

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Linoleic acid hydroperoxide reacts with hypochlorous acid, generating peroxyl radical intermediates and singlet molecular oxygen.

The reaction of hypochlorous acid (HOCl) with hydrogen peroxide is known to generate stoichiometric amounts of singlet molecular oxygen [O2 (1Deltag)]. This study shows that HOCl can also react with linoleic acid hydroperoxide (LAOOH), generating O2 (1Deltag) with a yield of 13 +/- 2% at physiological pH. Characteristic light emission at 1,270 nm, corresponding to O2 (1Deltag) monomolecular dec...

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Conversion of Linoleic Acid Hydroperoxide to Hydroxy,

We have carried out a study of the reaction of 13Irydroperoxy-9-cis, 11-trans-octadecadienoic acid (linoleic acid hydroperoxide) with hematin. The major products are erythro-ll-hydroxy-l2,13-epoxy-S-octadecenoic acid, threo11-hydroxy12,13-epoxy-9-0~tadecenoic acid, 9,12,13-trihydroxy-lO-octadecenoic acid, 13-keto-9,ll-octadecadienoic acid, and 13-hydroxy-9,ll-octadecadienoic acid. Several minor...

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Reaction of linoleic acid hydroperoxide with thiobarbituric acid.

The linoleic acid hydroperoxide obtained by enzymatic peroxidation of linoleic acid was found to react with thiobarbituric acid to yield a red pigment. The optimum pH for the reaction was found to be 4.0. In the early stages of peroxidation of linoleic acid, thiobarbituric acid value, the amount of conjugated diene, oxygen consumption, and peroxide value were in parallel with one another. The d...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 2002

ISSN: 0264-6021

DOI: 10.1042/0264-6021:3610057